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Symbol
Name
ID
Ptgs2
prostaglandin-endoperoxide synthase 2
MGI:97798
Phenotype annotations related to respiratory system
Darker colors indicate more annotations
Human Phenotypes
Sinusitis
Chronic sinusitis
Pleural effusion
Chylothorax
Pulmonary arterial hypertension
Recurrent pneumonia
Asthma
Recurrent respiratory infections
Recurrent bronchopulmonary infections
Recurrent lower respiratory tract infections
Bronchoconstriction
Dyspnea
Exertional dyspnea
Abnormal lung morphology
Elevated bronchoalveolar lavage fluid neutrophil proportion
Abnormal pleura morphology
Pneumothorax
Pulmonary fibrosis
Usual interstitial pneumonia
Emphysema
Alveolar cell carcinoma
Hemoptysis
Bronchiectasis
Decreased DLCO
Decreased forced expiratory flow 25-75%
Reduced forced expiratory volume in one second
Reduced forced vital capacity
Airway hyperresponsiveness
Airway obstruction
Chronic pulmonary obstruction
Upper airway obstruction
Chronic lung disease
Cough
Hyperpolarized transepithelial nasal potential difference
Disease(s) Associated with PTGS2
asthma
chronic obstructive pulmonary disease
cystic fibrosis
idiopathic pulmonary fibrosis
sarcoidosis

Mouse Phenotypes
pulmonary interstitial fibrosis
Availability Mouse Genotype
Ptgs2tm1Jed/Ptgs2tm1Jed

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory